Prenatal Prediction of the Type of Omphalocele Closure by Different Medical Consultants

Nina Peters, ME Visser t Hooft, Alex Eggink, Dick Tibboel, Nicolette Ursem, Rene Wijnen, Gouke Bonsel, Titia Overbeek

Research output: Contribution to journalArticleAcademicpeer-review


Introduction: To evaluate differences between consultants of different disciplines in the prenatal prediction of the type of postnatal surgical closure of an omphalocele. Material and Methods: Twenty-one images of prenatally detected omphaloceles prior to 24 weeks of gestation were included. A standardized form provided known prenatal information and an ultrasound image for each case. Nineteen consultants were asked to assess the probability of primary closure of an omphalocele and to state which information was the most important for their assessment. Results: Primary closure (13/21 images) was predicted correctly in 5/13 images. The number of correct predictions per image ranged from 63 to 89%. The type of closure was predicted correctly in 7/8 images of cases which were not closed primarily, ranging from 58 to 84% correct predictions per image. There was no significant difference between consultants of different disciplines. Individual accuracy ranged from 10 to 62%. The consultants regarded omphalocele content as the most important information (34%) for counseling. Discussion: The consultants did not differ in their prenatal judgment of the primary closure of an omphalocele. The consultants tended to be too negative in their assessment, since 75% assessed the probability of primary closure overall to be <60%, whereas 62% of the cases were primarily closed. Omphalocele content was the most important information for the consultants' judgment. (C) 2015 S. Karger AG, Basel
Original languageUndefined/Unknown
Pages (from-to)40-49
Number of pages10
JournalFetal Diagnosis & Therapy
Issue number1
Publication statusPublished - 2016

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