Vitamin D and Physical Performance in Older Men and Women Visiting the Emergency Department Because of a Fall: Data from the Improving Medication Prescribing to reduce Risk Of FALLs (IMPROveFALL) Study

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ObjectivesTo investigate whether serum 25-hydroxy vitamin D (25(OH)D) is associated with physical performance in men and women. DesignCross-sectional. SettingEmergency departments (EDs) of five hospitals. ParticipantsOlder adults who visited an ED because of a fall (N=616). MeasurementsPhysical performance was assessed using the Timed Up and Go Test, the Five Time Sit to Stand Test, handgrip strength, and the tandem stand test. Multivariate linear regression was used to assess the association between physical performance and log-transformed 25(OH)D concentration adjusted for potential confounders. ResultsIn men, higher serum 25(OH)D concentration was significantly associated with better handgrip strength (regression coefficient (B)=3.86, 95% confidence interval (CI)=2.04-5.69), faster TUG time (B=-2.82, 95% CI=-4.91 to -0.73), and faster FTSS time (B=-3.39, 95% CI=-5.67 to -1.11). In women, higher serum 25(OH)D concentration was significantly associated with faster TUG time (B=-2.68, 95% CI=-4.87 to -0.49). ConclusionA positive association was found between serum 25(OH)D level and physical performance in men and women. Intervention studies are needed of vitamin D-deficient older men and women to further investigate the effect of vitamin D supplementation in this group.
Original languageUndefined/Unknown
Pages (from-to)1948-1952
Number of pages5
JournalJournal of American Geriatrics Society
Issue number11
Publication statusPublished - 2013

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